WebMar 21, 2024 · HCC1806: Synonyms: Hcc1806; HCC-1806; Hamon Cancer Center 1806: Accession: CVCL_1258: Resource Identification Initiative: To cite this cell line use: HCC1806 (RRID:CVCL_1258) Comments: Group: Triple negative breast cancer (TNBC) cell line. Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line … WebMay 31, 2024 · Also remarkably, in the partially resistant HCC1806 cells with strong cyclin E1 expression, p16 was absent due to deletion of the CDKN2A locus (Cosmic database). ... Hennecke S, Amati B (1997) Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins.
TRIPLE NEGATIVE BREAST CANCER PANELS - ATCC
WebOct 11, 2024 · We describe the pharmacodynamics and efficacy of PF-06873600 (PF3600), a pyridopyrimidine with potent inhibition of CDK2/4/6 activity and efficacy in multiple in … WebApr 6, 2024 · Cyclin E1 expression in these models was comparable to expression in the HGSOC model CaOv3 which lacks CCNE1 amplification. One BLBC cell line with high … dog tick medication
Trials with CDK inhibitors in TNBC. Download ... - ResearchGate
WebWe have focused on the role of cyclin E in determining the virulence and metastatic potential of tumor cells. 4-8 In normal dividing cells, cyclin E regulates the transition from the G 1... Web( E) HCC1806-shRNA cyclin E cells were subjected to high through put survival analysis with increasing concentrations of PARPi (MK-4827) for 48 h as shown in Figure S2A and were immunoblotted (inset) with the indicated antibodies. Web(E) MIT suppressed HCC1806 cell proliferation and promoted apoptosis in vivo. Tumors collected from saline control and MIT groups were paraffin-fixed, sliced and stained with anti-ki-67 or... fairfax nursing home va