Foxf1-as1
WebMar 11, 2024 · Loss of long noncoding RNA FOXF1-AS1 regulates epithelial-mesenchymal transition, stemness and metastasis of non-small cell lung cancer cells [26]. Long noncoding RNA XIST acts as an oncogene in non-small cell lung cancer by epigenetically repressing KLF2 expression [27]. In this study, we found that lncRNA FOXD2-AS1 is highly … WebApr 12, 2024 · As an example, the lncRNA Fendrr is transcribed divergently from the transcription factor FOXF1. ... LINC00844, RP3-332B22.1, UNC5B-AS1, RP11-557H15.4, and RP11-432J24.5) were differentially expressed in AF patients compared to normal subjects. The signaling pathways associated with these lncRNAs were the calcium …
Foxf1-as1
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WebAnd we identified that lncRNA FOXF1-AS1 was a single antisense oligonucleotide RNA transcribed from the negative strand of Forkhead box protein F1 (FOXF1) and concordantly up-regulated with FOXF1 in osteosarcoma cell lines and tissues. Besides, our data showed that FOXF1-AS1 can serve as a biomarker to predict the prognosis of OS patients. WebFOXF1-AS1 promoted OS cell proliferation, migration, invasion and tumor growth in vitro and vivo. (A) FOXF1-AS1 expression in MG63 and 143B cells after si-RNA or vector transfection. (B) CCK-8 assays were …
WebOct 18, 2016 · LncRNA FOXF1-AS1 was lowly expressed in tissue samples from NSCLC patients To identify novel lncRNAs in non-small cell lung cancer (NSCLC), we profile … WebStable overexpression of FOXF1-AS1 inhibits lung cancer cell migration and invasion by regulating EMT. Meanwhile, loss of FOXF1-AS1 mediates stem-like properties of lung …
WebMar 21, 2024 · Results suggest that long noncoding RNA FOXF1-AS1 might regulate epithelial-mesenchymal transition (EMT), stemness and metastasis of non-small cell lung cancer (NSCLC) cells via EZH2, indicating it as a therapeutic target for future treatment of NSCLC. FENDRR plays an important role in the progression and metastasis of gastric … WebFeb 19, 2024 · LncRNA fetal-lethal non-coding developmental regulatory RNA (FENDRR), also named as FOXF1-AS1, is an intergenic lncRNA with consisting of seven exons. It is located at 3q13.31, 1,354 bp upstream of transcriptional start site, which is transcribed from a bidirectional promoter shared with the protein coding gene Foxf1 and Pitx2.
WebFOXF1-AS1. FOXF1-AS1 acts as a tumor suppressor RNA as its loss mediates cancer stemness along with enhanced EMT. FOXF1-AS1 was shown to target PRC2 complex …
WebInterestingly, FOXF1-AS1 was found to not affect gastric cancer cell proliferation, a phenotype unexplored in the study by Miao et al. and one which would be valuable to evaluate in the context of lung cancer cells. The authors also reported FOXF1-AS1 to be a regulator of epithelial-mesenchymal transition (EMT) in NSCLC cells. how i thwipped my summer vacation wikiWebMay 30, 2024 · FENDRR, also known as lncRNA FOXF1-AS1, is located at chromosomal band 3q13.31 and transcribed from the FOXF1 promoter and co-expressed with FOXF1 gene. 14 Khalil et al first identified FENDRR and confirmed its chromatin-modifying complex-binding ability. 15 As an important tumor-repressor gene, FENDRR was selected as an … how i thwipped my summer vacationWebAdditionally, miR-1253 mimic or GSK343, a FOXF1 inhibitor, was respectively transfected into VSMCs with p-FOXC2-AS1. Results showed that the promoted cell proliferation and inhibited cell apoptosis were reversed as well, confirming that FOXC2-AS1 promoted cell proliferation and inhibited apoptosis via miR-1253/FOXF1 signaling axis in AS patients. how itil helpsWebNov 15, 2024 · It is increasingly evident that non-coding RNAs play a significant role in tumour development. However, we still have a limited knowledge of the clinical significance of long non-coding RNAs (lncRNAs) in lung cancer. The FENDRR is a long coding RNA (also named FOXF1-AS1) located in the vicinity of t how i tickWebAnd we identified that lncRNA FOXF1-AS1 was a single antisense oligonucleotide RNA transcribed from the negative strand of Forkhead box protein F1 (FOXF1) and … how it intrinsically worksWebJan 1, 2024 · Micro-RNAs (miRs) are a class of endogenously expressed non-coding RNAs that negatively regulate gene expression within cells and participate in maintaining cellular homeostasis. By targeting 3’... how it impacts the environmentWebThis protein is a transcription factor, which means that it attaches (binds) to specific regions of DNA and helps control the activity of many other genes. The FOXF1 protein is … how it invest in bitcoin