Fgf13 cancer
WebExpression of FGF13 in cancer - Summary - The Human Protein Atlas FGF13 PATHOLOGY CANCER Dictionary Human pathology PROGNOSTIC SUMMARYi Gene … WebApr 9, 2024 · Innovate through Integrated Solutions Home; Contact Us; English Deutsch; 日本語; 简体中文; Products. Product Browser; Product Discounts & Benefits
Fgf13 cancer
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WebJul 24, 2024 · Deletion of Fgf13 in a MMTV-PyMT breast cancer cell line reduces colonization of the lungs in a tail vein injection. In addition, loss of Fgf13 reduced in vitro cell migration, suggesting that ... WebSep 2, 2024 · Fibroblast growth factor 13 (FGF13) is aberrantly expressed in multiple cancer types, suggesting its essential role in tumorigenesis. Hence, we aimed to explore …
WebFGF13, a member of the FGF subfamily, has been found to be highly expressed in cancer cells such as prostate cancer, melanoma, glioma and multiple myeloma. However, the mechanism of FGF13 function during cancer cell proliferation remains to be unexplored, especially Non-small cell lung cancer (NSCLC). WebThe up-regulation of miR-10b suppressed the growth, colony formation, migration and invasion of CRC cell. Furthermore, the xenograft model indicated that miR-10b inhibited CRC cell growth and lung metastasis in vivo by targeting fibroblast growth factor 13 (FGF13). In addition, we demonstrated that the overexpression of FGF13 rescued the ...
WebProstate cancer is the second leading cause of cancer death in males in the United States. Metastatic prostate cancer has a five-year survival rate of 31%. Although many genes involved in prostate tumor development have been identified, the exact role that they play in tumor progression or metastasis is unclear. CD82, a WebJun 29, 2024 · A 5'-UTR SNP of FGF13 impairs PTBP2 interacting with FGF13 mRNA, leading to reduced FGF13 translation and deficits in brain development and cognitive functions. ... a G>C mutation in BRCA1 5′-UTR was identified in a highly aggressive sporadic breast cancer and resulted in a defective initiation of BRCA1 protein translation …
WebImportantly, in cancer cells expressing high levels of FGF13, the depletion of FGF13 elicits increased proteostasis stress, associated with the accumulation of reactive oxygen …
WebFunctional assays indicated that FGF9 protein synthesis was normally controlled by uORF-mediated translational repression, which kept the protein at a low level, but was upregulated in response to hypoxia through a switch to IRES-dependent translational control. Our data demonstrate that FGF9 IRES functions as a cellular switch to turn FGF9 ... prince of persia latestWebJan 4, 2024 · PIM1 is a serine/threonine kinase that promotes and maintains prostate tumorigenesis. While PIM1 protein levels are elevated in prostate cancer relative to local disease, the mechanisms by which ... please wipe your shoes off signs imagesWebFibroblast growth factor homologous factors (FHFs) belong to the fibroblast growth factor (FGF) superfamily, which plays an important role in prostate cancer (PCa). Mining of public database suggests that FGF13 (FHF2) mRNA expression is altered in … please windWebFGF13, also known as fibroblast growth factor homologous factor-2 (FHF2), is an intracellular protein that binds to the C-terminal domain of voltage-gated sodium channels to modulate their function and location. FHFs are not secreted by cells and have only a limited ability to activate FGF receptors (summary by Fry et al., 2024 ). please withdrawWebOct 11, 2013 · Cancer cells often develop drug resistance. In cisplatin-resistant HeLa cisR cells, fibroblast growth factor 13 (FGF13/FHF2) gene and protein expression was strongly upregulated and intracellular ... please with a cherry on top memeWebApr 4, 2024 · FGF13 Is Required for Histamine-Induced Itch Sensation by Interaction with NaV1.7. E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 … please with a cherry on top in spanishWeb中国科学院上海生命科学研究院植物生理生态研究所合成生物学重点实验室 prince of persia level 5 life potion