WebBlood dendritic cell antigen 2 (BDCA-2) is a human-specific pDC-type II C-type lectin that potently inhibits IFN secretion. Here we determined the effects of CBS004, a novel monoclonal antibody against BDCA-2, on Toll-like receptor (TLR)-induced transcriptome and IFN secretion in pDCs from healthy volunteers (HV) or patients with SSc in vitro ... WebLe groupe BDCA est implanté historiquement à Toulon puis a développé sa présence sur Hyères, Antibes et Nice. Entrepreneur par nature, Bruno Dartiguenave a été gérant de …
CD304 (BDCA-4) Antibody, anti-human - Miltenyi Biotec
Webfunctional characterization of BDCA-2. BDCA-2 is a novel type II C-type lectin presumably involved in ligand internalization, processing and presentation, as well as in inhibition of IFN-/ synthesis in PDCs. Our results identify BDCA-2 as an attractive pharmaceutical target for specific downmodulation of IFN-/ expression in pa-tients with SLE. WebThe proportions of BDCA-2- and BDCA-3-expressing cells in SLE PBMCs were reduced compared with those in PBMCs from healthy controls (P = 0.01 and P = 0.004, respectively). IFN alpha producers in culture, especially among SLE PBMCs, displayed reduced BDCA-2 expression and constituted only a minority of the BDCA-2-positive cells, at least in ... shaquille o\u0027neal\u0027s home in mcdonough ga
Monoclonal antibody targeting BDCA2 ameliorates skin lesions in ...
WebCD303 (BDCA-2) antibodies have been used, for example, to identify, characterize, and enumerate plasmacytoid dendritic cells in whole blood of healthy and HIV-infected individuals, and for analyzing the role of DC-SIGN in HIV infection and transmission.7,11 Furthermore, CD303 (BDCA-2) antibodies were used to identify and enumerate … WebCD303, also known as BDCA-2 and CLEC4C, is a 38 kD type II transmembrane glycoprotein. It is a member of the C-type lectin superfamily. CD303 is expressed by plasmacytoid dendritic cells (pDCs) and is involved in cell adhesion, signaling, and antigen capture and processing. Crosslinking of CD303 inhibits the production of IFN-α/β and … Webaddress: les terriers nord immeuble les sporades 500 allee des terriers 06600, antibes, provence alpes cote d azur france Phone: ? Website: www.bdca.fr pool builders manatee county